Preparation of a low-dust free-flowing choline chloride powder

US4820532A · kind A · utility

Assignee

• BASF SE

Inventors

• Robert Bayer · Sinsheim, DE
• Guenter Boettger · Bad Dürkheim, DE
• Rainer Hiller · Munster, DE
• Michael Huber · Bissenkamp, SE
• Wolfgang Koernig · Dossenheim, DE
• Wolfgang Fritz · Karlsruhe, DE

Key dates

• Filing date: Jun 30, 1987
• Grant date: Apr 11, 1989
• Expiry date: Jun 30, 2007

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/148
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A low-dust, free-flowing choline chloride powder based on natural carriers or silica, the choline chloride content on natural carriers being from 30 to 60% by weight and that on silica being from 30 to 80% by weight, based on the choline chloride powder, is prepared by a process in which PA0 (a) choline chloride solution is mixed with the carrier in the desired ratio within the stated range, PA0 (b) the resulting mixture is sprayed continuously into a fluidized bed already containing dry choline chloride powder and is dried there at from 90.degree. to 180.degree. C., and PA0 (c) the dried end product is removed from the fluidized bed and cooled to below 50.degree. C.