Antimicrobial aromatic derivatives substituted by an (omega amino) alkanol group and compositions containing them
US4820717A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 30, 1986 |
| Grant date | Apr 11, 1989 |
| Priority date | — |
| Expiry date | Sep 30, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/524
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to new aromatic derivatives of formula: ##STR1## wherein: Alk is an alkylene group with 1 to 10 carbon atoms, PA0 R.sub.1 is hydrogen or an alkyl with 1 to 6 carbon atoms, PA0 R.sub.2 and R.sub.3 are similar or different and represent a cycloalkyl with 3 to 6 carbon atoms or a striaght or branched alkyl with 1 to 6 carbon atoms, either substituted or non-substituted by a phenyl or methyl phenyl group, or R.sub.2 and R.sub.3 form, together with the atom of nitrogen to which they are bonded, a mono-nitrogenous heterocycle containing no other heteroatom, such as pyrrolidino, piperidino, azepino, hexamethylene-imino, 4-methyl-piperidino, 4-phenyl-piperidino, 1,2,3,4-tetrahydro-2-isoquinolyl, 4-benzyl-piperidino; PA0 R.sub.4 is hydrogen, halogen, methyl or phenyl, PA0 R.sub.5 is hydrogen, halogen or methyl, PA0 or R.sub.4 and R.sub.5 together with the benzene ring to which they are bonded, constitute a 1-naphthyl or 2-naphthyl group, PA0 and the pharmaceutically acceptable salts with mineral or organic acids. The invention compounds possess interesting antimicrobial properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.