Analogs of [1,7-di-alanine, des-19-leucine]calcitonin
US4820804A · kind A · utility
3Cited by
10References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 1987 |
| Grant date | Apr 11, 1989 |
| Priority date | — |
| Expiry date | Apr 21, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New hypocalcaemic peptides are disclosed of the formula ##STR1## wherein X represents H for the replacement of the N alpha amino group or acyl groups for the acylation of the N alpha amino group, the N-alpha amino group. The acyl groups are carboxylic acids especially formic, acetic, propionic, buteric, valeric, hexanoic, heptanoic, octanoic, and nonanoic acids or their respective isomers, L-lactic acid and the half amides of malonic, succinic, glutaric and adipic acids. Y is L-valine, glycine, L-methionine, L-alanine, L-leucine or L-isoleucine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.