Novel pyridazinone-imines and their physiologically tolerated addition salts with acids, their preparation and therapeutic agents containing these compounds

US4820821A · kind A · utility

Assignee

• BASF SE

Inventors

• Rudolf Kropp · Schifferstadt, DE
• Marco Thyes
• Rainer Schlecker · Bissersheim, DE
• Albrecht Franke
• Franz Reicheneder
• Dora I. Reicheneder · Ludwigshafen, DE
• August Amann
• Hans-Juergen Teschendorf · Dudenhofen, DE
• Rolf Kretzschmar · Havelsee, DE
• Martin Traut · Heidelberg, DE
• Josef Gries · Monsheim, DE

Key dates

• Filing date: Apr 17, 1987
• Grant date: Apr 11, 1989
• Expiry date: Apr 17, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D237/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel 1-phenyl-4(1H)-pyridazinone-imines of the formula (I) ##STR1## which are substituted at the imine nitrogen, and their addition salts with a physiologically tolerated acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs, in particular as antidepressants, antiparkinson drugs and antihypotonic agents.