Method of large scale growth of toxoplasmic microorganisms
US4824666A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 13, 1987 |
| Grant date | Apr 25, 1989 |
| Priority date | — |
| Expiry date | Nov 13, 2007 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56905
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of producing large scale growth of parasites of the genus Toxoplasma is disclosed which comprises inoculating the microorganisms into a non-adherent human cell line, such as a monocytoid lymphoma cell line, and maintaining the cell line in tissue culture media capable of supporting the growth of the microorgranism while the cell line is being maintained. This large scale production allows for the development of vaccines for Toxoplasma microorganisms which previously have been hard to grow in the numbers needed to readily prepare vaccines, and allows for more rapid antibody detection procedures with regard to these microorganisms. There are also disclosed methods for preparing such vaccines, and methods for carrying out antibody detection assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.