Spiro (4,5) decone compounds
US4824836A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 20, 1988 |
| Grant date | Apr 25, 1989 |
| Priority date | — |
| Expiry date | May 20, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Spiro (4,5) decane compounds of the formula: ##STR1## in which: X is methyl and PA1 Y is hydrogen or R'--CO-- in which R' is C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, ##STR2## X and Y together represent ##STR3## in each of which A is hydrogen, methyl, carboxy, methoxycarbonyl or ethoxycarbonyl; PA1 R is C.sub.1 -C.sub.7 -alkyl optionally containing a double bond; PA1 Z is a C.sub.2 -C.sub.7 -polymethylene chain optionally carrying an OH group; PA1 R.sub.1 is hydrogen or methyl; and PA1 R.sub.2 is hydrogen, R'--CO-- or benzyloxycarbonyl; PA1 and physiologically tolerable acid addition salts thereof. These compounds may be used therapeutically especially in the treatment of asthma, allergic phenomena and bronchopathies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.