Pyrazoline compounds compositions and use
US4824859A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 1984 |
| Grant date | Apr 25, 1989 |
| Priority date | — |
| Expiry date | May 3, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are described compounds of formula I, ##STR1## in which Ar.sub.1 and Ar.sub.2, which may be the same or different, each independently represent phenyl or pyridinyl, the phenyl or the pyridinyl each optionally being substituted by one or more of halogen; hydroxy; --COOR.sub.12 ; trihalomethyl; alkoxy C1 to 6; alkyl C1 to 6; --NR.sub.1 R.sub.2 ; alkoxy C1 to 6 substituted by --NR.sub.1 R.sub.2 or by phenyl; or alkyl C1 to 6 substituted by --NR.sub.1 R.sub.2 or by --COOR.sub.12 ; PA1 R.sub.1 and R.sub.2, which may be the same or different, each independently represent hydrogen or alkyl C1 to 6, PA1 R.sub.3 represents hydrogen, alkyl C1 to 6, alkanoyl C1 to 6, benzoyl, --COOR.sub.8, or --CONHR.sub.11, PA1 R.sub.4, R.sub.5, R.sub.6 and R.sub.7, which may be the same or different each independently represent hydrogen, alkyl C1 to 6 or phenyl, PA1 R.sub.8 represents alkyl C1 to 6 or aryl, PA1 R.sub.11 represents alkyl C1 to 6 or aryl, PA1 R.sub.12 represents hydrogen or alkyl C1 to 6, and pharmaceutically acceptable derivatives thereof. There are also described compositions containing the compounds and methods for their preparation. The compounds are indicated for use as pharmaceuti…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.