4'-Methyl-.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid vasopressin antagonists
US4826813A · kind A · utility
2Cited by
6References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 1987 |
| Grant date | May 2, 1989 |
| Priority date | — |
| Expiry date | May 21, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Vasopressin antagonists which have a 4'-methyl-.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid group have vasopressin antagonist activity without substantial agonist activity. A species of the invention is [1-(4'-methyl-.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)-2-(O-ethyl)-D-tyrosine-4-valine-8-arginine]vasopressin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.