Cerebral function enhancing diazinylpiperidine derivatives
US4826843A · kind A · utility
6Cited by
4References
36Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 28, 1987 |
| Grant date | May 2, 1989 |
| Priority date | — |
| Expiry date | Aug 28, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A series of diazinylpiperidine compounds of Formula I ##STR1## wherein X is an ethylene chain or a 1,2-benzo ring; Y is carbonyl or methylene; R.sup.1 is hydrogen or lower alkyl; and Z is an R.sup.2, R.sup.3 -disubstituted diazinyl ring selected from pyridazine, pyrimidine, and pyrazine ring systems. Pharmacologic and neuroanatomical testing demonstrates that compounds of the series act to enhance cerebral function in mammals, particularly when there is a deficit in normal cerebral functioning. Specific pharmacologic test results indicate that compounds of Formula I possess cognition and memory enhancing activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.