Tetrachlororaffinose and its use in the preparation of sucralose
US4826962A · kind A · utility
15Cited by
6References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 20, 1986 |
| Grant date | May 2, 1989 |
| Priority date | — |
| Expiry date | Oct 20, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H5/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The novel chlorinated sugar O-.alpha.-D-6-chloro-6-deoxygalactopyranosyl-(1.fwdarw.6)-.alpha.-D-4-chlo ro-4-deoxygalactopyranosyl-(1.fwdarw.2)-.beta.-D-1, 6-dichloro-1, 6-dideoxyfructofuranoside (TCR) can be used to prepare sucralose by incubating the TCR in solution in the presence of an enzyme serving to remove the 6-chloro-6-deoxygalactosyl moiety from the 6-position, especially an enzyme derived from a strain of Mortierella vinacea, Circinella muscae or Aspergillus niger. TCR is prepared by treating raffinose with thionyl chloride in the presence of triphenylphosphine oxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.