Patent · US Expired

Nucleotide analogs for nucleic acid labeling and detection

US4828979A · kind A · utility

306Cited by
7References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 8, 1984
Grant dateMay 9, 1989
Priority date
Expiry dateNov 8, 2004

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/68
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Nucleotide analogs, modified by the attachment at hydrogen bonding positions of linker groups, that is, the 6-position of adenine, 4-position of cytosine, and 2-position of guanine, are prepared. Such analogs, alone or with reporter groups attached, may be incorporated into DNA probes which effectively hybridize to target DNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.