Patent · US Expired

1-(4-Hydroxy-3,5-di-tert.-butylbenzoyl)homopiperazine, various derivatives thereof, processes for the preparation of these compounds, medicaments containing them, and their use

US4829061A · kind A · utility

7Cited by

2References

9Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Erhard Wolf · Hofheim, DE
Erhard Rossmanith · Schwalbach am Taunus, DE
Robert R. Bartlett · Darmstadt, DE
Rudolf Schleyerbach · Hofheim, DE

Key dates

Filing date	Jan 28, 1988
Grant date	May 9, 1989
Priority date	—
Expiry date	Jan 28, 2008

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P37/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

1-(4-Hydroxy-3,5-di-tert.-butylbenzoyl)homopiperazine and various derivatives thereof substituted on the nitrogen are prepared starting from 4-hydroxy-3,5-di-tert.-butylbenzoic acid or its derivatives and homopiperazine or appropriate derivatives thereof. The compounds and their physiologically tolerated acid addition salts are suitable for the treatment of inflammatory and painful, in particular inflammatory rheumatic, disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.