Novel dihydropyridines having calcium antagonistic and antihypertensive activity
US4829076A · kind A · utility
18Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 16, 1987 |
| Grant date | May 9, 1989 |
| Priority date | — |
| Expiry date | Sep 16, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new substituted dihydropyridine derivatives of the general formula (I), ##STR1## wherein R.sup.1 and R.sup.6 are as defined herein after, the racemic and optically active variants as well as mixtures thereof, furthermore the acid addition salts of these compounds, pharmaceutical compositions containing the same and a process for the preparation thereof. The compounds of the general formula (I) can be advantageously applied for the treatment of pathologically severe hypertensions, their toxicity is low and they possess an advantageous therapeutic index.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.