Stressed polymeric device for controlled release of a substance to an ambient environment
US4830860A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 30, 1986 |
| Grant date | May 16, 1989 |
| Priority date | — |
| Expiry date | Oct 30, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A matrix device for controlled release of at least one active agent to an ambient environment, said matrix comprising an active agent--or agents--containing polymer which has been subjected to tensile stress. Included is a laminate device comprising at least one matrix as core sheet, said core sheet or sheets comprising the active agent or agents in a polymer matrix which has been subjected to stress and, in a further embodiment, a porosity enhancing agent in admixture with said agent; the core sheet or sheets being alternately sandwiched or interposed between coextensive inert polymeric films substantially impermeable to said environment and to said agent or agents, said device being perforated by one or a plurality of macroholes extending through said sheets and said films. Also included are methods for making such a device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.