Dopaminergic benzimidazol-2-ones
US4831043A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 12, 1988 |
| Grant date | May 16, 1989 |
| Priority date | — |
| Expiry date | Feb 12, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel benzimidazol-2-ones of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms, alkenyl and alkynyl of 3 to 5 carbon atoms with the multiple bond not between the carbons .alpha.- and .beta.- to the nitrogen and aralkyl of 7 to 12 carbon atoms optionally substituted with at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 5 carbon atoms and R.sub.1 is selected from the group consisting of hydrogen, --OH, alkoxy of 1 to 5 carbon atoms, phenoxy and phenylalkoxy of 7 to 9 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having dopaminergic, antiulcerous, and antihypertensive and vasodilatatory activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.