Antigenic polysaccharide specific to Brucella abortus and Yersinia enterocolitica serotype 0:9
US4831126A · kind A · utility
11Cited by
9References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1985 |
| Grant date | May 16, 1989 |
| Priority date | — |
| Expiry date | Feb 26, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The antigenic O-chain polysaccharides from Brucella abortus and Yersinia enterocolitica serotype 0:9 have similar structure, i.e. 1-2 linked 4,6-dideoxy-4-formamido-.alpha.-D-mannopyranosyl units. The antigen is more readily isolated from the Yersinia and may be chemically modified to have a hydrophobic moiety attached thereto. The antigen can be adsorbed or coupled to carriers suitable for immunoassay use such as ELISA and RIA. A monoclonal antibody capable of specifically binding to B. abortus and Y. enterocolitica, has been produced. Assay procedures and kits therefor, are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.