Method for administering interleukin-2
US4832686A · kind A · utility
Inventor
Key dates
| Filing date | Jun 24, 1986 |
| Grant date | May 23, 1989 |
| Priority date | — |
| Expiry date | Jun 24, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/2013
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biocompatible, biodegradable, bioerodible composite polymer matrix comprising interleukin-2 in an appropriate polymer. The polymer may be a polymer or copolymer of lactic acid, lactide, glycolide, glutamic acid, or it may be collagen or albumin. The material contains from 10.sup.2 to 10.sup.8 U IL-2/g of polymer. Also disclosed is a method for making the composite polyer matrix and a method for implanting the material. A soft, malleable controlled-release composite material may be used for intracranial or other implantation and may be shaped or molded to fit the site from which malignant tissue has been removed, opposing the residual tumor, complementing hemostasis, compatible with anatomical structure, and functioning as an implantable immunotherapeutic adjuvant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.