Patent · US Expired

Galenic forms of prolonged release verapamil and medicaments containing them

US4832958A · kind A · utility

31Cited by

0References

32Claims

0Family size

Assignee

Pharlyse S.A. Societe Anonyme · LU

Inventors

Philippe Baudier · Waterloo, BE
Arthur De Boeck · Herne, BE
Jacques Fossion · Braine-l'Alleud, BE

Key dates

Filing date	Sep 30, 1986
Grant date	May 23, 1989
Priority date	—
Expiry date	Sep 30, 2006

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/275
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The new galenic forms of prolonged release verapamil consist of microgranules containing a pharmacologically acceptable acid-addition salt or verapamil as active substance combined with at least one wetting agent, said microgranules being coated with a microporous membrane consisting of at least one pharmacologically acceptable adjuvant (such as plasticizer, filler, lubricant, etc) and of at least one film forming mixture composed of (1) at least one insoluble acrylic or methacrylic polymer and (2) a substance which is insoluble in the acid gastric medium, but soluble in the intestine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.