4-[4-[[2-(halophenyl)-2-[1H-tr:azol(or diazol)-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine-1-carbi mic acids having antimycotic activity

US4833141A · kind A · utility

Assignee

• Heumann Pharma GmbH · DE

Inventors

• Helmut Schickaneder · Eckental, DE
• Rolf Herter · Schwabach, DE
• Hartmut Vergin · Nuremberg, DE
• Heidrun Engler · Cadolzburg, DE
• Kurt H. Ahrens · Nürnberg, DE

Key dates

• Filing date: Jul 2, 1987
• Grant date: May 23, 1989
• Expiry date: Jul 2, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/56
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new 1,4-piperazine compounds corresponding to the following general formula ##STR1## which show improved antimycotic activity in relation to the known compounds miconazol and ketoconazol.