Two part tissue irrigating solution
US4837021A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 31, 1986 |
| Grant date | Jun 6, 1989 |
| Priority date | — |
| Expiry date | Dec 31, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A tissue irrigating solution useful for irrigating animal tissue, such as ocular tissue and neuro tissue, during surgery, contains sodium, potassium, magnesium calcium chloride, and bicarbonate ions as well as dextrose, glutathione, and gamma-amino butyric acid (GABA) or functional analogue(s) of GABA, or a mixture of GABA and such analogue(s) in proportions consistent with the osmotic stability and continued metabolism of the tissue cells. The irrigating solution is prepared by mixing a first basic solution which provides the bicarbonate and a second acidic solution which provides the calcium, magnesium, dextrose and glutathione. The first and second solutions may be stored as stable, sterile solutions for extended periods of time and mixed within 24 hours of use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.