Patent · US Expired

Methods of treating tumors susceptible to necrosis

US4837221A · kind A · utility

21Cited by
3References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 26, 1987
Grant dateJun 6, 1989
Priority date
Expiry dateMar 26, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/22
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides for therapy of tumours susceptible to necrosis by a porphyrin when an appropriate porphyrin compound is administered to locate in the tumor followed by illumination with light of a wavelength absorbed by the compound, making use of meso-porphyrins of the formula: ##STR1## where n=1 to 3 and each substitutent R, the same or different and at the same or different position in its respective substituent phenyl ring or other aromatic group replacing that ring, is an hydroxy, amino or sulphydryl group, by association of said meso-porphyrins with a suitable pharmaceutical diluent or carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.