Indole and indazole keto sulphones as leukotriene antagonists
US4837235A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 16, 1986 |
| Grant date | Jun 6, 1989 |
| Priority date | — |
| Expiry date | Oct 16, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides a series of novel keto sulfones of formula I ##STR1## in which the group .dbd.A-- is selected from .dbd.C(Ra)-- and .dbd.N-- and the other radicals have the meanings defined in the following specification. The compounds of formula I are leukotriene antagonists. The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compound, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.