Quinoline derivatives
US4837329A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 18, 1984 |
| Grant date | Jun 6, 1989 |
| Priority date | — |
| Expiry date | Jan 18, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing dihydro compounds of formula I, by rearranging compounds of formula II, e.g. in the presence of acids or noble metal catalysts, is described. The compounds II may be prepared from intermediates of formula III. ##STR1## In these formulae R.sup.1,R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are the same or different and represent hydrogen, or alkyl, cycloalkyl, aralkyl, or aryl radicals any of which radicals may be substituted, or R.sup.1 and R.sup.2 taken together or R.sup.2 and R.sup.3 taken together, form a 5, 6 or 7 membered ring which may be saturated or unsaturated and substituted or unsubstituted, R.sup.4 and R.sup.5 may also represent alkoxy, or cycloalkoxy, n is 1, 2 or 3 and, if more than one R.sup.4 radical is present the R.sup.4 radicals may be the same or different and R.sup.6 and R.sup.7 represent hydrogen, alkyl, cycloalkyl, or aralkyl radicals. Most of the compounds I, II and III are novel and are claimed. They are intermediates for anti-ulcer agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.