Antibody preparations
US4841025A · kind A · utility
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15Claims
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Key dates
| Filing date | Mar 21, 1988 |
| Grant date | Jun 20, 1989 |
| Priority date | — |
| Expiry date | Mar 21, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/808
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A monoclonal antibody preparation having a single binding activity, which activity is in respect of a cell surface antigen, comprises IgG antibody molecules in which only one of the two light chains will bind to said antigen, the proportion of such antibody molecules being enhanced relative to IgG antibody molecules having two light chains which will bind to said antigen to thereby produce an enhancement of the binding activity of the preparation. Such preparations containing predominatly "monovalent antibodies" are of particular value in the areas of transplantation immunity, the treatment of neoplastic disease and cell sorting.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.