Covalently bonded active agents with carbonium ion base groups
US4842868A · kind A · utility
Inventor
Key dates
| Filing date | Sep 26, 1986 |
| Grant date | Jun 27, 1989 |
| Priority date | — |
| Expiry date | Sep 26, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D319/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a unique set of compositions of matter characterized by including defined active agents covalently bonded to carbonium ion base groups, as well as the method of creating the compositions. The covalently bonded compositions include base groups in the nature of ketene acetals and vinyl ethers and the thio equivalents thereof. The available active agents include alcohols, phenols, carboxylic acids, thiols, amines, amides, urethanes, phosphate esters, sulfonic acids and oximes. The compositions may either be in capped form or leashed to a polymeric backbone. The compositions are ordinarily formed by self actuating reactions when the appropriate base groups and active agents are juxtaposed under proper environmental conditions. The primary uses of the compositions are in controlled release applications such as drugs, topical insecticides and the like or in any application where predictable hydrolytic release of the active agent is desirable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.