1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof
US4843082A · kind A · utility
3Cited by
6References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 5, 1986 |
| Grant date | Jun 27, 1989 |
| Priority date | — |
| Expiry date | May 5, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Leukotriene biosynthesis in macrophage cells is inhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 and R.sub.2 are each hydrogen and R.sub.3 is alkyl or arylalkyl; PA1 R.sub.1 and R.sub.3 are each hydrogen and R.sub.2 is arylmethyl or arylcarbonyl; PA1 R.sub.1 is methyl, R.sub.2 is arylmethyl and R.sub.3 is hydrogen; or PA1 R.sub.1 is alkyl of seven or more carbons or arylalkyl and R.sub.2 and R.sub.3 are each hydrogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.