Patent · US Expired

[2,2,1]Cryptand compounds that selectively bind sodium

US4843158A · kind A · utility

10Cited by
0References
5Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 19, 1986
Grant dateJun 27, 1989
Priority date—
Expiry dateNov 19, 2006

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/84
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A compound having the property of selectively binding sodium ions in the presence of potassium ions and having the formula: ##STR1## where X is ##STR2## and where any aromatic ring may be substituted and/or may form part of a fused aromatic ring system. At least one of the aromatic rings may be substituted by a spectroscopic reporter group, a group which permits the compound to enter and remain in a cell and/or an electron donating or withdrawing group. A method of determining cytoplasmic sodium concentration by using this compound as a probe is also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.