DNA sequences coding for proteins having the biological activity of HUSI-type I inhibitors, biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins

US4845076A · kind A · utility

Assignee

• GRUNENTHAL GMBH · DE

Inventors

• Regina Heinzel · Aachen, DE
• Heribert Appelhans · Trautheim, DE
• Hans G. Gassen · Darmstadt, DE
• Werner Machleidt · Munich, DE
• Ursula Seemuller · Munich, DE

Key dates

• Filing date: Jan 9, 1987
• Grant date: Jul 4, 1989
• Expiry date: Jan 9, 2007

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are described DNA sequences from the genome of mammals, in particular from the human genome, coding for proteins having the biological activity of HUSI-type I inhibitors. There are further described biotechnological methods of the preparation of proteins having the biological activity of HUSI-type I inhibitors as well as pharmaceutical compositions containing said proteins.