Substituted 3-amino-sydnonimines, their use and pharmaceutical products containing them

US4845091A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Karl Schonafinger · Alzenau, DE
• Rudi Beyerle · Frankfurt, DE
• Helmut Bohn · Schöneck, DE
• Melitta Just · Langen, DE
• Piero Martorana · Bad Homburg vor der Höhe, DE
• Rolf-Eberhard Nitz · Frankfurt am Main, DE

Key dates

• Filing date: Jul 14, 1986
• Grant date: Jul 4, 1989
• Expiry date: Jul 14, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Optically active substituted 3-aminosydnonimines of the general formula I ##STR1## and their pharmacologically acceptable acid addition salts, wherein R.sup.1 denotes, for example, the radical R.sup.3 (R.sup.4)N-, PA0 R.sup.2 denotes the radical 1-methoxyethyl (--CH(CH.sub.3)OCH.sub.3), acetoxy-phenyl-methyl (--CH(C.sub.6 H.sub.5)O--COCH.sub.3), 1-(ethoxycarbonyl)-ethoxy (--O--CH.sub.3)CO.sub.2 C.sub.2 H.sub.5), PA0 R.sup.3 denotes alkyl(C.sub.1 -C.sub.4) and PA0 R.sup.4 denotes for example alkyl(C.sub.1 -C.sub.4), possess valuable pharmaceutical properties.