Tetrahydroquinoline derivatives, their use and pharmaceutical formulations containing them

US4845099A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Wolfgang Ruger · Alfeld, DE
• Gerd Driesen · Wiesbaden, DE
• Helmut Bohn · Schöneck, DE
• Piero Martorana · Bad Homburg vor der Höhe, DE

Key dates

• Filing date: Sep 22, 1987
• Grant date: Jul 4, 1989
• Expiry date: Sep 22, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Derivatives of tetrahydroquinoline of the formula I ##STR1## and acid addition salts thereof, wherein n denotes 2, 3, 4, 5 or 6, R.sup.1 denotes, for example, alkyl, phenyl or pyridyl, R.sup.2 denotes the radical ##STR2## R.sup.3 and R.sup.4 independently of one another denote, for example, hydrogen, alkyl or cycloalkyl and R.sup.5 denotes, for example, hydrogen, alkyl or phenyl, have useful pharmacological properties.