Anti-allergy treatment using 2-(substituted amino)-4,5-dihydro-4-oxo-3-furancarboxylic acids and derivatives thereof
US4845122A · kind A · utility
Inventors
Key dates
| Filing date | Dec 5, 1986 |
| Grant date | Jul 4, 1989 |
| Priority date | — |
| Expiry date | Dec 5, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
As an anti-allergic treatment for warm-blooded animals, therapeutic amounts of a compound having the formula I (including acid salts thereof) or II are administered: ##STR1## where; R is OR.sup.4 or NHR.sup.5 in which R.sup.4 is hydrogen or lower alkyl, R.sup.5 is selected from phenyl and phenyl monosubstituted with halogen, lower alkyl, lower alkoxy, R.sup.1 and R.sup.2 are independently hydrogen or lower alkyl, and PA1 R.sup.3 is selected from lower alkyl, arylcyclopropyl, naphthyl, phenyl, and phenyl monosubstituted with lower alkyl, lower alkoxy, trifluoromethyl, halogen, nitro, carboxyl, or ethyl carboxylate; ##STR2## R.sup.6 is lower alkyl, R.sup.7 is selected from phenyl and phenyl monosubstituted with lower alkyl, lower alkoxy, halogen or acetyl, and M is an alkali or alkaline earth metal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.