Glycopeptide recovery process
US4845194A · kind A · utility
11Cited by
19References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 1987 |
| Grant date | Jul 4, 1989 |
| Priority date | — |
| Expiry date | Feb 27, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K9/008
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An improvement in the large-scale recovery of vancomycin-type glycopeptide antibiotics which comprises (1) commingling the fermentation medium in which the antibiotic is produced with a polystyrene divinylbenzene resin such as Dow XFS-43278.00, (2) separating the resin from the medium and (3) eluting the antibiotic from the resin. This improvement avoids preliminary filtration and pH adjustment of the broth, simplifies waste-disposal problems and eliminates antibiotic losses due to mycelial adsorption and filtration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.