Patent · US Expired

Inhibitor of ribonucleotide reductase

US4845195A · kind A · utility

9Cited by
0References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 22, 1987
Grant dateJul 4, 1989
Priority date
Expiry dateMay 22, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2710/16622
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides containing the foregoing pentapeptide sequence are more potent inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.