Nitrogen- and sulfur-containing lipid compounds their production and use
US4845219A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1987 |
| Grant date | Jul 4, 1989 |
| Priority date | — |
| Expiry date | Jul 23, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the general formula [I]: ##STR1## wherein R.sub.1 represents a higher alkyl group or an N-(higher alkyl)carbamoyl group, R.sub.2 represents a lower alkyl group, an acyl group having at least three carbon atoms, an N-(lower alkyl)carbamoyl group, an N-(lower alkyl)thiocarbamoyl group or a benzyl group, R represents a primary, secondary or tertiary amino group or a quaternary ammonium group, x is 1 or 2, y is a number of 0, 1 or 2, and z is an integer of 2-10, or a pharmaceutically acceptable salt thereof. The novel substances have both anti-tumor activity and platelet activating factor-inhibiting property, and they are effective as an anti-tumor agent without circulatory trouble.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.