Acylation process for the synthesis of HMG-CoA reductase inhibitors
US4845237A · kind A · utility
4Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1987 |
| Grant date | Jul 4, 1989 |
| Priority date | — |
| Expiry date | Apr 15, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel acylation process using an alkali metal bromide and a dialkylaminopyridine to form a sterically hindered ester functionality from an alkanoyl chloride and an alcohol is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.