Method of preparing 4-trifluoromethyl-2-nitrobenzoic acid and novel isomer
US4845279A · kind A · utility
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7Claims
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Key dates
| Filing date | Dec 22, 1987 |
| Grant date | Jul 4, 1989 |
| Priority date | — |
| Expiry date | Dec 22, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C205/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An isomer mixture of 4-trifluoromethyl-2-nitrobenzoic acid and 4-trifluoromethyl-3-nitrobenzoic acid, which is a novel compound, is obtained by nitrating a compound represented by ##STR1## (Z is COY or CY.sub.3, and Y is a halogen atom) with a nitrating agent comprising nitric acid and simultaneously hydrolyzing the radical Z. Each of the two isomers is easily isolated by treating the mixture with a basic neutralizing agent to obtain a solution containing the 2-nitro isomer and a precipitate containing the 3-nitro isomer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.