Method for promoting tissue adhesion to soft tissue implants
US4846834A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1988 |
| Grant date | Jul 11, 1989 |
| Priority date | — |
| Expiry date | Mar 16, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2310/00407
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A soft tissue implant comprises a flexible main body portion, having tissue-facing surfaces and a thin layer of pure titanium covering the tissue-facing surfaces. A method of promoting tissue adhesion of a soft tissue host to the tissue-facing surfaces of a soft tissue implant comprising a strip of polyethylene terephthalate velour comprises the steps of cleaning the strip with a low-residue detergent and rinsing same with fresh distilled water; refluxing the strip in distilled water for one hour at a temperature of less than 30.degree. C.; drying the strip in a room-temperature desicator for several days; sterilizing the strip and packaging same; degasing the strip and storing same in a dust-free environment; removing the strip from the packaging and mounting the strip in a vacuum evaporator at an approximate angle of incidence of 90.degree. from a pure titanium metal evaporant; evacuating the vacuum evaporator to a vacuum of about 2.times.10.sup.-5 Torr; evaporating the titanium by direct resistence heating same; coating the strip with a layer of pure titanium on the order of one micron thick; and resterilizing and implanting the titanium-coated strip into the tissue host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.