Patent · US Expired

Tert-butylphenyl compounds useful as anti-inflammatory agents

US4847303A · kind A · utility

4Cited by
6References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 23, 1987
Grant dateJul 11, 1989
Priority date
Expiry dateNov 23, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C49/835
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention involves compounds having the structure: ##STR1## wherein: (a) --A.sup.1 is selected from the group consisting of --OH, --H, and --O.sub.2 CR; PA1 (b) --A.sup.2 is selected from the group consisting of unsubstituted or substituted, saturated or unsaturated, straight, branched and cyclic alkyl having from 1 to about 10 carbon atoms; PA1 (c)--A.sup.3 is selected from --C(CH.sub.3).sub.3, --Si(CH.sub.3).sub.3, and --CF.sub.3 ; and PA1 (d) --Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: ##STR2## and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.