Production of 3-allyl- and 3-butenyl-3-cephems
US4847373A · kind A · utility
9Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1987 |
| Grant date | Jul 11, 1989 |
| Priority date | — |
| Expiry date | Feb 26, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D501/59
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is disclosed a process for the production of certain 2-allyl- and 3-butenyl-3-cephem derivatives by coupling a 3-chloromethyl-3-cephem with a hydrocarbyltributystannane in the presence of bis(dibenzylideneacetonyl)-palladium and a phosphine. The 3-allyl- and 3-butenyl-3-cephem derivatives so-produced are useful as broad-spectrum antibacterial agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.