Antibacterial 1,8-bridged 4-quinoline-3-carboxylic acids

US4847375A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Klaus Grohe · Odenthal, DE
• Michael Schriewer · Odenthal, DE
• Hans-Joachim Zeiler · Velbert, DE
• Karl G. Metzger · Wuppertal, DE

Key dates

• Filing date: Jun 13, 1986
• Grant date: Jul 11, 1989
• Expiry date: Jun 13, 2006

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

As antibacterials and animal growth promoters, the compounds of the formula ##STR1## in which Y is --COOH, --COOR.sup.7 or --CONR.sup.8, R.sup.9, PA1 X.sup.1 is H, nitro, alkyl or halogen, PA1 R.sup.10 and R.sup.11 preferably complete a piperazine ring, PA1 Z is oxygen or NR.sup.15, PA1 n is 0 or 1, and PA1 the others can have various meanings, and pharmaceutically acceptable hydrate, alkali metal, alkaline earth metal, silver or guanidinium salt or ester thereof.