Recovery of L-amino acid isomers from their racemic mixtures
US4847409A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1988 |
| Grant date | Jul 11, 1989 |
| Priority date | — |
| Expiry date | Dec 14, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the isolation of a substantially pure L-isomer of an amino acid from its D,L racemic mixture does not require the use of a resolving agent, the formation of a derivative of the amino acid or additional enzymic reactions.The method is based upon the concept of the equal saturation point wherein the L-isomer can be separated from the D-isomer by precipitation of the L-isomer when the relative concentration of the D-isomer is less than 7.0% or by precipitation of the D,L racemate when the relative concentration is greater than 7.0%. Selective crystallization through seeding allows for further isolation of pure L-isomer when its relative concentration in solution is very low.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.