Patent · US Expired

Method and apparatus for liquid chromatography

US4849110A · kind A · utility

20Cited by
15References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 1987
Grant dateJul 18, 1989
Priority date
Expiry dateNov 12, 2007

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N30/34
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention relates to a liquid chromatography based on a very small liquid feeding rate, where a liquid sample containing components to be detected, such as anion species, is mixed with an eluting solution, the resulting liquid mixture is continuously passed through a separation column, whereby the components to be detected are held in the separation column, then a predetermined amount of an extraction liquid as an aliquot is injected into the stream of the liquid mixture, and the liquid mixture is continuously passed through the separation column after the injected extraction liquid has passed through the separation column. The thus obtained chromatogram has peaks corresponding to the consumptions of the components to be detected in the liquid mixture. According to the present invention the unpractical problem that a very trace amount of a liquid sample has been so far injected when a flow rate of the eluting solution is low can be completely solved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.