Method for producing sustained release formulation
US4849141A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 24, 1986 |
| Grant date | Jul 18, 1989 |
| Priority date | — |
| Expiry date | Dec 24, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2018
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing a sustained release formulation utilizing collagen and/or gelatin as a carrier, which comprises the steps: PA0 (i) preparing a uniform and high concentrated mixture with respect to the collagen and/or gelatin by blending an active ingredient, said collagen and/or gelatin, and water or an admixture consisting of water and a hydrophilic organic solvent under one of the conditions selected from: PA1 (A) the pH of the mixture is kept below 5 and the salt concentration of the mixture is retained below fiber-forming concentration; PA1 (B) chemically modified collagen and/or gelatin is employed; and PA1 (C) glucose is added to the mixture; PA0 (ii) molding the resultant mixture; and PA0 (iii) gradually eliminating the solvent from the molded product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.