Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors

US4851440A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Gerhard Beck · Frankfurt am Main, DE
• Peter Below · Frankfurt, DE
• Andreas Bergmann · Berlin, DE

Key dates

• Filing date: Jul 22, 1988
• Grant date: Jul 25, 1989
• Expiry date: Jul 22, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors. Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X have the indicated meanings, processes for the preparation of these compounds, the use thereof as pharmaceuticals, and pharmaceutical products based on these compounds are described. In addition, precursors for the preparation of compounds of the formula I are described.