Separation of citric acid from fermentation broth with a weakly basic anionic exchange resin adsorbent
US4851573A · kind A · utility
27Cited by
1References
21Claims
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Key dates
| Filing date | Nov 16, 1987 |
| Grant date | Jul 25, 1989 |
| Priority date | — |
| Expiry date | Nov 16, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/47
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Citric acid is separated from a fermentation broth by using an adsorbent comprising a water-insoluble macroreticular or gel weakly basic anionic exchange resin possessing tertiary amine functional groups or pyridine functional groups, said anionic exchange resin comprising a cross-linked acrylic or styrene resin matrix. Citric acid is desorbed by water or dilute sulfuric acid. The pH of the feed is maintained below the first ionization constant (pKa.sub.1) of citric acid to maintain selectivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.