N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylg lycine S-oxide and the amide thereof
US4853484A · kind A · utility
1Cited by
2References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 28, 1987 |
| Grant date | Aug 1, 1989 |
| Priority date | — |
| Expiry date | Oct 28, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylgly cine S-oxide (tolrestat S-oxide) and the amide thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.