Process for the preparation of (2,2)-paracyclophane and derivatives thereof
US4853488A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 8, 1988 |
| Grant date | Aug 1, 1989 |
| Priority date | — |
| Expiry date | Apr 8, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/92
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the preparation of (2,2)-paracyclophane or derivatives thereof by the Hofmann elimination of p-methylbenzyl-trimethylammonium hydroxide or derivatives thereof, in an aqueous solution of an alkali metal hydroxide, wherein said elimination is carried out in the presence of a compound of the formula (I): EQU (R).sub.m --A--(X).sub.n (I) wherein A represents an aromatic group, X an electron donor group, R hydrogen or an alkyl group containing from 1 to 4 carbon atoms, n is an integer from 1 to 6, and m is zero or an integer from 1 up to a value such that the sum m+n is equal to the number of substitutable positions in the aromatic group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.