Renin-inhibiting di- and tripeptides, a process for their preparation, agents containing them, and their use

US4855286A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Adalbert Wagner · Gersthofen, DE
• Heinz-Werner Kleemann · Bischofsheim, DE
• Dieter Ruppert · Kronberg, DE
• Bernward Scholkens · Kelkheim, DE

Key dates

• Filing date: Jul 28, 1987
• Grant date: Aug 8, 1989
• Expiry date: Jul 28, 2007

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/86
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of the formula ##STR1## in which R.sup.1 is absent or denotes hydrogen, alkyl or acyl, A denotes an acyl radical or an amino acid residue, B denotes an amino acid residue, and R.sup.2, R.sup.3 and R.sup.4 are as defined in the specification, and to their salts, to a process for their preparation, to pharmaceutical products containing them, and to their use as medicaments, and intermediates for the preparation of these compounds.