Method for reducing skin irritation associated with drug/penetration enhancer compositions
US4855294A · kind A · utility
181Cited by
2References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 6, 1988 |
| Grant date | Aug 8, 1989 |
| Priority date | — |
| Expiry date | Sep 6, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition and method for reducing the skin irritation properties of a transdermal drug/enhancer composition which comprises incorporating into said composition, either prior to or at the time of application the skin, an effective amount of glycerin. When incorporated into the drug/enhancer composition prior to application to the skin the glycerin content will be between about 0.1 and 70 wt. %, preferably between about 1.0 and 50 wt. % and most preferably between about 5.0 and 20 wt. % of the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.