Certain azaspirodecane compounds and a method of inducing an anxiolytic activity
US4855302A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1987 |
| Grant date | Aug 8, 1989 |
| Priority date | — |
| Expiry date | Dec 10, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound selected from the group consisting of azaspirodecane derivatives of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, fluorine, chlorine, bromine, alkoxy of 1 to 3 carbon atoms, --NO.sub.2, --NH.sub.2 and CH.sub.3 S-- in the 4,5 or 6 position of the ring, R' is oxo or hydrogen or --OH or alkyl of 1 to 3 carbon atoms and the dotted line indicates a carbon-carbon bond in the 2,3-position, n is 2,3,4 or 5 and the dotted line in the piperidyl ring is an optional carbon-carbon bond and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anxiolytic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.